Photo by: Taris Smith | Louisville Athletics
Second Half Comeback Fuels Cards Victory Over Virginia Tech
November 01, 2025 | Football
Blacksburg, Va. — The No.16-ranked University of Louisville football team (7-1, 4-1 ACC) outscored Virginia Tech, 21-0, in the second half to secure a 28-16, come from behind victory on Saturday at Lane Stadium.
Trailing 16-7 in the third quarter, Louisville receiver Caullin Lacy hauled in a 24-yard touchdown pass from Miller Moss to cut the lead to 16-14.
The Cards defense would force a punt on the next Hokies possession, which Lacy would return 63 yards to the five-yard-line. Louisville running back Keyjuan Brown would punch it in for a two-yard touchdown a couple of plays later to give the Cards a 21-16 lead.
UofL's defense pitched a second half shutout. The Cardinals forced Virginia Tech into five punts and a turnover on downs in the second half. UofL's defense had a combined five tackles-for-loss. Senior linebacker T.J. Quinn led the Cards defense with 10 tackles.
Moss finished the game 19-of-28 for 136 yards, while adding one touchdown through the air.
Louisville running back Isaac Brown had 126 yards on the ground, including a 52-yard rushing touchdown. Keyjuan Brown added 94 rushing yards, while punching in two touchdowns. This is the second consecutive week the pair has combined for 200+ rushing yards.
Louisville Football Head Coach Jeff Brohm said this:
"Definitely proud of our football team today. I thought we showed great grit, great toughness. It was a disappointing first half overall and I think we all felt that it was a little bit down going into the locker room (at half), including myself and the players, and we could tell that. So, we just had to take a couple of deep breaths, understand there is still 30 minutes of football to play, we can play better if we just got out there and believe in ourselves and not take our foot off the gas. I think for the most part we did that. We played hard and made enough plays in the second half to win, we would like to play cleaner, but that's football in conference games and against good teams. There's plenty of things to improve. These guys have grit and want to win, so its fun coaching them."
How It Happened
First Quarter
12:58 – UL – Isaac Brown went 52 yards untouched for the opening score. 2 plays, 62 yards, 0:34. Louisville 7, Virginia Tech 0
01:57 – VT – Kyren Drones kept it himself for a 3-yard touchdown. 9 plays, 37 yards, 4:56. Louisville 7, Virginia Tech 7
00:52 – VT – P.J. Prioleau blocked the Louisville punt out of the end zone for a safety. Virginia Tech 9, Louisville 7
Second Quarter
08:25 – VT – Kyron Drones hit Cameron Seldon for a 5-yard touchdown. 8 plays, 54 yards, 3:33. Virginia Tech 16, Louisville 7
Third Quarter
09:07 – UL – Miller Moss hit Caullin Lacy over the middle for a 24-yard score. 6 plays, 53 yards, 2:55. Virginia Tech 16, Louisville 14
05:01 – UL – Keyjuan Brown cashed in a great Caullin Lacy punt return with a 2-yard touchdown run. 2 plays, 5 yards, 0:41. Louisville 21, Virginia Tech 16
Fourth Quarter
05:57 – UL – Keyjuan Brown dashed in for a 24-yard rushing touchdown. 7 play, 63 yards, 3:41. Louisville 28, Virginia Tech 16
Up Next
The Cards head back home to host ACC foe, California. The game will be a 7 p.m. ET kick inside L&N Stadium.
Trailing 16-7 in the third quarter, Louisville receiver Caullin Lacy hauled in a 24-yard touchdown pass from Miller Moss to cut the lead to 16-14.
The Cards defense would force a punt on the next Hokies possession, which Lacy would return 63 yards to the five-yard-line. Louisville running back Keyjuan Brown would punch it in for a two-yard touchdown a couple of plays later to give the Cards a 21-16 lead.
UofL's defense pitched a second half shutout. The Cardinals forced Virginia Tech into five punts and a turnover on downs in the second half. UofL's defense had a combined five tackles-for-loss. Senior linebacker T.J. Quinn led the Cards defense with 10 tackles.
Moss finished the game 19-of-28 for 136 yards, while adding one touchdown through the air.
Louisville running back Isaac Brown had 126 yards on the ground, including a 52-yard rushing touchdown. Keyjuan Brown added 94 rushing yards, while punching in two touchdowns. This is the second consecutive week the pair has combined for 200+ rushing yards.
Louisville Football Head Coach Jeff Brohm said this:
"Definitely proud of our football team today. I thought we showed great grit, great toughness. It was a disappointing first half overall and I think we all felt that it was a little bit down going into the locker room (at half), including myself and the players, and we could tell that. So, we just had to take a couple of deep breaths, understand there is still 30 minutes of football to play, we can play better if we just got out there and believe in ourselves and not take our foot off the gas. I think for the most part we did that. We played hard and made enough plays in the second half to win, we would like to play cleaner, but that's football in conference games and against good teams. There's plenty of things to improve. These guys have grit and want to win, so its fun coaching them."
How It Happened
First Quarter
12:58 – UL – Isaac Brown went 52 yards untouched for the opening score. 2 plays, 62 yards, 0:34. Louisville 7, Virginia Tech 0
01:57 – VT – Kyren Drones kept it himself for a 3-yard touchdown. 9 plays, 37 yards, 4:56. Louisville 7, Virginia Tech 7
00:52 – VT – P.J. Prioleau blocked the Louisville punt out of the end zone for a safety. Virginia Tech 9, Louisville 7
Second Quarter
08:25 – VT – Kyron Drones hit Cameron Seldon for a 5-yard touchdown. 8 plays, 54 yards, 3:33. Virginia Tech 16, Louisville 7
Third Quarter
09:07 – UL – Miller Moss hit Caullin Lacy over the middle for a 24-yard score. 6 plays, 53 yards, 2:55. Virginia Tech 16, Louisville 14
05:01 – UL – Keyjuan Brown cashed in a great Caullin Lacy punt return with a 2-yard touchdown run. 2 plays, 5 yards, 0:41. Louisville 21, Virginia Tech 16
Fourth Quarter
05:57 – UL – Keyjuan Brown dashed in for a 24-yard rushing touchdown. 7 play, 63 yards, 3:41. Louisville 28, Virginia Tech 16
Up Next
The Cards head back home to host ACC foe, California. The game will be a 7 p.m. ET kick inside L&N Stadium.
Team Stats
UL
VT
Total Yards
371
240
Pass Yards
136
76
Rushing Yards
235
164
Penalty Yards
52
46
1st Downs
18
16
3rd Downs
4
4
4th Downs
0
0
TOP
30:22
29:38
1st Quarter

UL 7, VT 0
UL - Brown,Isaac 52 yd run (Ranvier,Cooper kick), 2 plays, 62 yards, TOP 00:42

UL 7, VT 7
VT - Drones,Kyron 3 yd run (Love,John kick), 9 plays, 37 yards, TOP 04:56

UL 7, VT 9
VT - 0 yd safety
2nd Quarter

UL 7, VT 16
VT - Seldon,Cameron 5 yd pass from Drones,Kyron (Love,John kick) 8 plays, 54 yards, TOP 03:40
3rd Quarter

UL 14, VT 16
UL - Lacy,Caullin 24 yd pass from Moss,Miller (Ranvier,Cooper kick) 6 plays, 53 yards, TOP 02:55

UL 21, VT 16
UL - Brown,Keyjuan 2 yd run (Ranvier,Cooper kick), 2 plays, 5 yards, TOP 00:41
4th Quarter

UL 28, VT 16
UL - Brown,Keyjuan 24 yd run (Ranvier,Cooper kick), 7 plays, 67 yards, TOP 03:41
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