2016 Louisville Football Box Scores
| Date | Opponent | Location | Result | Stats |
|---|---|---|---|---|
| 09/01/16 | Charlotte | Louisville, Ky. | W, 70-14 | Box Score |
| 09/09/16 | Syracuse | Syracuse, N.Y. | W, 62-28 | Box Score |
| 09/17/16 | #2 Florida State | Louisville, Ky. | W, 62-20 | Box Score |
| 09/24/16 | Marshall | Huntington, W.Va. | W, 59-28 | Box Score |
| 10/1/16 | #5 Clemson | Clemson, S.C. | L, 36-42 | Box Score |
| 10/14/16 | Duke | Louisville, Ky. | W, 24-14 | Box Score |
| 10/22/16 | NC State | Louisville, Ky. | W, 54-13 | Box Score |
| 10/29/16 | Virginia | Charlottesville, Va. | W, 32-25 | Box Score |
| 11/5/16 | Boston College | Chestnut Hill, Mass. | W, 52-7 | Box Score |
| 11/12/16 | Wake Forest | Louisville, Ky. | W, 44-12 | Box Score |
| 11/17/16 | Houston | Houston, Texas | L, 10-36 | Box Score |
| 11/26/16 | Kentucky | Louisville, Ky. | W, 38-41 | Box Score |
| 12/31/16 | LSU | Orlando, Fla. | L, 9-29 | Box Score |
