University of Louisville
2021 Football Schedule
Overall6-70.462
Conference4-40.500
StreakL2
Home4-3
Away2-2
Neutral0-2
| Date | Time | At | Opponent | Location | Tournament | Result |
|---|---|---|---|---|---|---|
| Sep 6 (Mon) | 8:00 PM ET | Neutral | Mississippi | Atlanta, Ga. | L 24-43 | |
| Sep 11 (Sat) | 7:00 PM ET | Home | Eastern Kentucky | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | W 30-3 | |
| Sep 17 (Fri) | 7:30 PM ET | Home | UCF | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | W 42-35 | |
| Sep 25 (Sat) | 3:30 p.m. | Away | Florida State | Tallahassee, FL | W 31-23 | |
| Oct 2 (Sat) | 12:30 p.m. | Away | #24 Wake Forest | Winston-Salem, NC | L 34-37 | |
| Oct 9 (Sat) | 3 p.m. | Home | Virginia | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | L 33-34 | |
| Oct 23 (Sat) | 4 p.m. | Home | Boston College | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | W 28-14 | |
| Oct 30 (Sat) | 7:30 p.m. | Away | NC State | Raleigh, NC | L 13-28 | |
| Nov 6 (Sat) | 7:30 PM | Home | Clemson | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | L 24-30 | |
| Nov 13 (Sat) | 12:00 p.m. | Home | Syracuse | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | W 41-3 | |
| Nov 18 (Thu) | 7:30 p.m. | Away | Duke | Durham, NC | W 62-22 | |
| Nov 27 (Sat) | 7:30 p.m. | Home | Kentucky | LOUISVILLE, KY (L&N Federal Credit Union Stadium) | L 21-52 | |
| Dec 28 (Tue) | 3:15 PM | Neutral | Air Force | Dallas, Texas | ServPro First Responder Bowl | L 28-31 |